Psychologic stress, anemia, parasitic infestations, hypothyroidism, hyperthyroidism and diabetes are considered as other offenders that increase the risk of alopecia areata that may progress to Alopecia Universalis. Apart from autoimmunity, experts believe that Alopecia Universalis may also be caused due to genetic inheritance, factors such as viral infection or environmental triggers. Since the condition originates from alopecia areata it also seems to share the causative factors. Interestingly the targeted antigen is private to the hair follicle in case of Alopecia Universalis. Its association with other autoimmune disorders such as vitiligo, lichen planus, morphea, atopic dermatitis, and diabetes mellitus confirms that Alopecia Universalis may be caused when body’s immune system mistakenly attacks the healthy hair follicles considering them as an antigen. However, since it is a progression of alopecia areata, Alopecia Universalis too seems to have strongest association with autoimmunity. The exact cause of Alopecia Universalis is not known yet. As per one study Alopecia Universalis usually appears before the age of 30 years. Hence, people who suffer from Alopecia Universalis show a high prevalence of mood, anxiety and depressive disorders.Īlopecia Universalis can affect adults as well as children. Loss of complete body hair can be cause of psychological disturbances.
The inflammatory markers such as pathogenic T-cells, cytokine and chemokine are thought to infiltrate the hair follicle bulb leading to hair loss.
The hair follicle damage that leads to total hair loss seems to be mediated through inflammation. Alopecia areata can progresses into alopecia totalis that causes complete loss of scalp hair or into Alopecia Universalis which results in total hair loss from scalp and other body parts such as face, pubic region, underarms, chest, hand and legs.
It is an autoimmune disorder that is considered as a severe form of alopecia areata, which causes small patches of diffuse hair loss on the scalp. What is Alopecia Universalis?Īlopecia Universalis is characterised by complete loss of hair on the scalp as well as other parts of the body. This article discusses the clinical features, aetiology and available treatment options for Alopecia Universalis. Since hair loss is of non-scarring type hair re-growth may be possible in some cases. Some experts also suspect involvement of environmental as well as genetic factors. The causes of Alopecia Universalis are not known, but it is thought to be an autoimmune disorder that occurs when body’s own immune system attacks hair follicles. About 1 to 2% people who develop alopecia areata show progression into Alopecia Universalis. Alopecia Universalis is thought to be a progression of alopecia areata that begins with round patches of hair loss on the scalp. Unlike other alopecia conditions that specifically affect the scalp hair, Alopecia Universalis results in hair loss from scalp as well as other hear bearing regions of the body. Alopecia Universalis: Causes, Symptoms and Treatment RichFeelĪlopecia Universalis is a condition in which there is complete loss of hair on the scalp and also all over the body.
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